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http://140.112.114.62/handle/246246/171266
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| Title: | Application of Gnrh Antagonist in Combination with Clomiphene Citrate and Hmg for Patients with Exaggerated Ovarian Response in Previous Ivf/Icsi Cycles |
| Authors: | 林育宏;蕭國明;謝碧純;黃莉文;黃詩嘉;陳芷郁;陳培欣;黃建榮
LIN, YU-HUNG;SEOW, KOK-MIN;HSIEH, BIH-CHWEN;HUANG, LEE-WEN;HUANG, SHIH-CHIA;CHEN, CHIH-YU;CHEN, PEI-HSIN;HWANG, JIANN-LOUNG |
| Contributors: | 眼科部 |
| Date: | 2007 |
| Issue Date: | 2009-10-21T07:43:46Z
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| Abstract: | Purpose: To investigate if the combination of clomiphene citrate, hMG, and cetrorelix (CC/hMG/cetrorelix protocol) can be applied to patients who had excessive response to GnRHa long protocol. Methods: Fifty patients who coasted and failed to conceive in their first cycles stimulated with GnRHa long protocol were stimulated with CC/hMG/cetrorelix protocol. The peak serum estradiol levels, the need of coasting and prolonged coasting ( >= 4 days), and the incidences of OHSS were compared. Results: The peak estradiol level was significantly lower with CC/hMG/ cetrorelix protocol compared to GnRHa long protocol. With CC /hMG/cetrorelix protocol, only four patients (8%) needed coasting and no one coasted >= 4 days. In contrast, in the first cycles, 11 patients (22%) needed coasting >= 4 days . The incidence of moderate OHSS was significantly lower with CC/hMG/ cetrorelix protocol. Conclusions: The CC/hMG/ cetrorelix protocol is an acceptable alternative protocol for patients who had excessive response to GnRHa long protocol. |
| Relation: | JOURNAL OF ASSISTED REPRODUCTION AND GENETICS v.24 n.8 pp.331-336 |
| Appears in Collections: | [附設醫院眼科部] 期刊論文
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