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| Title: | Effect of Radiation on the Cochlear Blood Flow in Guinea Pigs
放射線照射對天竺鼠耳蝸血流的影響 |
| Authors: | 譚慶鼎;林凱南;許權振;黃淑珍;曾鑠鑠
TAN, CHING-TING;LIN, KAI-NAN;HSU, CHUAN-JEN;HUANG, SHU-CHEN;TSENG, SHUO-SHUO |
| Contributors: | 耳鼻喉部 |
| Date: | 1994 |
| Issue Date: | 2009-10-14T11:43:26Z |
| Abstract: | Radiation for malignant head and neck tumors often affects the end organs of the fearing apparatus. The effect of radiation-induced vascular change may play an important role in the post-radiotherapy hearing loss. To evaluate the effect of irradiation on the cochlear blood flow, 12 fuinea pigs were irradiated in fractionatdion with a otal dosage of 5000 cGy of Co-60. Irradiation was given in 5 days per week, the daily dose being 200 cGy. The guinea pigs were sacrificed 10-12 months after the completion of irradiation. The cochlear blood flow was neasured with non- radioactive microspheres organ perfusion method. In comparison with similar age-matched non-irradiated guinea pigs, the cochlear blood flow of the irradiated group was significantly lower than the non-irradiated group.#0127# |
| Relation: | JOURNAL OF THE OTOLARYNGOLOGICAL SOCIETY, R.O.C. v.29 n.6 pp.441-446 |
| Appears in Collections: | [附設醫院耳鼻喉部] 期刊論文
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