Loading...
|
Please use this identifier to cite or link to this item:
http://ntur.lib.ntu.edu.tw/handle/246246/169016
|
| Title: | Plasma Interleukin-18 Levels in Hemodialysis Patients: Increased by Dialysis Process and Association with Interleukin-6 and Tumor Necrotic Factor-Alpha |
| Authors: | 姜至剛;黃政文;徐世平;何泰儀;白玫芬;彭渝森;劉興華;洪冠予;蔡敦仁
CHIANG, CHIH-KANG;HUANG, JENQ-WEN;HSU, SHIH-PING;HO, TAI-I;PAI, MEI-FEN;PENG, YU-SEN;LIU, SHING-HWA;HUNG, KUAN-YU;TSAI, TUN-JEN |
| Contributors: | 綜合診療部 |
| Date: | 2006 |
| Issue Date: | 2009-09-30T06:31:00Z |
| Abstract: | Background/Aims: This study investigated changes of interleukin-18 (IL-18 ) levels before and after dialysis, and the possible association with other pro-inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha). Methods: Plasma IL-18 of healthy controls, and pre- and post-dialysis of uremic patients undergoing hemodialysis (HD) were evaluated by ELISA methodology. Results: Plasma IL- 18 levels were significantly increased in patients with maintenance HD ( p < 0.001) compared to its level in normal subjects. When compared to pre- dialysis levels, a significant increase in plasma IL-18 was measured at the end of HD (p = 0.032). There was a significant correlation among plasma IL-18, 6 and TNF-alpha levels in HD patients. Conclusion: Plasma IL -18 concentration was significantly higher in HD patients and was significantly elevated by cellulose-based HD processes. Pre-activation of immunologically active cells may contribute to the association between pre -dialysis IL-18 and post-dialysis IL-6 and TNF-alpha levels. Copyright (c) 2006 S. Karger AG, Basel. |
| Relation: | BLOOD PURIFICATION v.24 n.2 pp.174-179 |
| Appears in Collections: | [附設醫院綜合診療部] Periodical Articles
|
Files in This Item:
There are no files associated with this item.
|
All items in NTUR are protected by copyright, with all rights reserved.
|
