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Please use this identifier to cite or link to this item: http://140.112.114.62/handle/246246/167864

Title: Urban Air Pollution Increases Plasma Fibrinogen and Plasminogen Activator Inhibitor-1 Levels in Susceptible Patients
Authors: 蘇大成;詹長權;廖朝崧;林亮宇;高憲立;莊凱任
SU, TA-CHEN;CHAN, CHANG-CHUAN;LIAU, CHIAU-SUONG;LIN, LIAN-YU;KAO, HSIEN-LI;CHUANG, KAI-JEN
Contributors: 內科部
Date: 2006
Issue Date: 2009-09-23T19:29:56Z
Abstract: Background: The cardiovascular effects on fibrinolytic activity by urban air pollution are still unknown. Methods: Paired fasting blood samples during high and low air pollution days in Taipei were taken from a panel of 49 patients with coronary heart disease or multiple risk factors to study their fibrinolytic and inflammatory response to urban air pollution. Paired t-tests and mixed- effects models were used to determine the air pollution effects. Results: Patients' plasma plasminogen activator inhibitor-1 levels were significantly increased when hourly concentrations of particulate matter with diameters less than 10 [mu]m (PM10) were greater than 100 [mu]g/m3 during the period 0800 to 1800 h. Conclusion: Urban air pollution has an adverse effect on plasma fibrinolytic function in a susceptible population.
Relation: EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION v.13 n.5 pp.849-852
Appears in Collections:[附設醫院內科部] 期刊論文

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